One for two

The new semi-auto­matic assembly machine for pens and auto-injec­tors stands out with its flex­i­bility. For the first time, two dif­ferent prod­ucts can be man­u­fac­tured on one plat­form – without the need for mechan­ical format changeovers. With this semi-auto­matic solu­tion, Harro Höfliger speeds up market access for their cus­tomers at an early stage.

(Photo: Helmar Lünig)


Pens and auto-injec­tors are assem­bled without mechan­ical format changeovers. If addi­tional ver­sions are to be processed, only a simple format change com­mand at the HMI will be required.


All crit­ical processes are auto­mated. Pressing and joining oper­a­tions as well as func­tion checks are fully mon­i­tored as with a high-per­for­mance system.


The semi-auto­matic machine also is equipped with Harro Höfliger’s proven Human Machine Inter­face (HMI). It goes without saying that it ful­fills the CFR part 11 require­ments for FDA-com­pliant elec­tronic sig­na­ture. Cus­tomers ben­efit from the com­pre­hen­sive ser­vice including ser­vice portal and remote maintenance.


The machine‘s proven GMP-com­pliant design makes oper­a­tion and cleaning easy. For manual loading, up to two oper­a­tors have direct access to the inser­tion point at the rotary table.


The illus­trated semi-auto­matic ver­sion achieves up to 56 parts per minute. For lab­o­ra­tory require­ments and for high output, addi­tional ver­sions are avail­able: With the lab-scale machine, up to ten single or multi format parts per minute can be assem­bled. Harro Höfliger’s port­folio also offers fully auto­matic machines with a capacity of up to 560 parts per minute.


The machine con­cept allows sub-sequent automa­tion at any time. For example, con­ver­sion from semi-auto­matic to fully auto­matic mode is pos­sible, in case of increasing pro­duc­tion demand. The inte­gra­tion of addi­tional tech­nolo­gies such as labelers, and con­nec­tions to down­stream equip­ment such as car­toning machines is also possible.

Two prod­ucts – one machine – no mechan­ical format changeover


With many years of expe­ri­ence in designing, devel­oping, man­u­fac­turing, and com­mer­cial­iza­tion of med­ical devices, BD sup­ports cus­tomers in the rapid market seg­ment of new prod­ucts. BD Phys­io­ject™, a dis­pos­able auto-injector (right), was devel­oped fol­lowing exten­sive studies and con­sid­ering user expe­ri­ence. It received the Ease of Use SM com­men­da­tion from the Arthritis Foun­da­tion ® for its ease of han­dling. The auto-injector can be used in com­bi­na­tion with BD Neopak™ and BD Hypak™ for Biotech 1ml Long pre­fill­able glass syringes. BD Vystra™ dis­pos­able pen is designed for simple and com­fort­able admin­is­tra­tion of liquid med­ical agents with vari­able dosing reg­i­mens. It can be cus­tomized according to cus­tomer-spe­cific requirements.

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Photos: Helmar Lünig