BEST PRACTICE  

Filling cap­sules globally

From trials to the pro­duc­tion of small series and test sam­ples up to high-speed pro­duc­tion of 200,000 cap­sules per hour – with the Modu‑C, Harro Höfliger offers cus­tomized solu­tions for every phase of the product. Indi­vid­u­ally devel­oped func­tions are not uncommon. We asked Modu‑C users on dif­ferent con­ti­nents how they uti­lize their Modu‑C.

Recep Ercanoglu

„For many years, Boehringer Ingel­heim has been relying on the tech­nology of Harro Höfliger. Our four Modu‑C HS for the dosing of pel­lets into cap­sules ful­fill our high demands for reli­a­bility and output.”Recep Ercanoglu, Tech­nology Coach Encap­su­la­tion, Boehringer Ingel­heim, Germany

Martin Wing-King

“As a leading CDMO of inhala­tion pow­ders, we pur­chased the Modu‑C LS in 2010 to increase our cap­sule filling capa­bil­i­ties. Having the machine onsite has def­i­nitely con­tributed to us win­ning addi­tional busi­ness in this area. The Modu‑C LS has enabled us to fill low fill weight cap­sules con­taining dif­fi­cult to handle pow­ders with very good filling RSDs.“Martin Wing-King, Director of Busi­ness Devel­op­ment and Project Management,Pharmaterials, United Kingdom

Hans-Peter Mennet

“Oper­ator safety in pro­duc­tion is a high pri­ority at Novartis. The Modu‑C LS Con­tain­ment com­bines safe han­dling of active ingre­dient con­taining powder with excel­lent ergonomic design.“Hans-Peter Mennet, Head Internal Supply, PHAD Orals, Novartis Tech­nical R&D, Switzerland

Dr. Nor­bert Rasenack

“The Modu‑C LS scores points with its extra­or­di­nary flex­i­bility – to us it is the first choice as a flex­ible cap­sule filling machine during tech­nical devel­op­ment.”Dr. Nor­bert Rase­nack, Head Process-Devel­op­ment & Equip­ment Engi­neering, Novel Oral Prod­ucts, Novartis Tech­nical R&D, Switzerland

Dr. Mohamed Shalaby

“Since we installed the Modu‑C MS we ­man­aged to fill our Food Sup­ple­ments Prod­ucts ­suc­cess­fully with RSD less than 0,9 % despite a fill weight up to 1.100 mg. Thanks to the Trolley con­cept, we decided to offer other cus­tomers our expe­ri­ence and ser­vices to fill tricky prod­ucts in cap­sules and to develop CMO busi­ness.”Dr. Mohamed Sha­laby, CEO, Ner­hadou, Egypt

Li Jewin

“The Modu‑C MS doses the inhala­tion powder very pre­cisely and effi­ciently. By means of the AMV system, the mass is deter­mined and the quality of our prod­ucts ensured.”Tiejun Li, Pres­i­dent, GM Shadong Jewim, China

Dr. Alek­sandr Malin

“We greatly appre­ciate the excel­lent part­ner­ship with Harro Höfliger and the highly sophis­ti­cated machine tech­nology. Ini­tially we started pro­duc­tion with a Modu‑C LS. Now we could easily transfer the processes to three faster Modu‑C MS machines. Excel­lent upscaling!”Dr. Alek­sandr Malin, CEO, Nativa, Russia

Pastor Bar­rios

“Since May 2014 we have been working with a Modu‑C MS with drum dosing and inte­grated AMV sensor. Throughout the entire project we worked very closely with the experts from Harro Höfliger, and we are very sat­is­fied with the machine.”Pastor Bar­rios, Chief of Elec­trical Engi­neering, Scavone Group, Eticos, Paraguay

Sal­va­tore Scimemi

“I would like to thank everyone for all their hard work and ded­i­ca­tion, not only for the pre­vious months but espe­cially for the two weeks that I have been onsite at Harro Höfliger. The com­mit­ment and ded­i­ca­tion you have shown to this project is remark­able. Not only have we assem­bled a team to solve issues and make progress, we had fun doing it.”Sal­va­tore Scimemi, Process Tech­nol­o­gist, Acorda Ther­a­peu­tics, USA


Fur­ther infor­ma­tion on the cap­sule filling machines:


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Illus­tra­tion: hernza/iStockphoto.com, Photos: Acorda Ther­a­peu­tics, Boehringer, GM Shadong Jewim, Nativa, Ner­hadou, Novartis, Phar­ma­te­rials, Scavone Group