Pressurized metered dose inhalers (pMDI) play an essential role in the treatment of various respiratory diseases. They contain active ingredient and propellant; when the device is actuated, an inhalable aerosol is released.
Together with Koura, a leading manufacturer of medical propellants, and the pMDI expert Pharmatec Solutions, Harro Höfliger is working on a special dosing technology. In this two-stage filling process, the container is first filled with the solid active ingredient and only in the second stage with the propellant. This enables exact dosing of API and facilitates the use of new, more climate-friendly propellants. The main focus of the collaboration is on joint proof-of-concept trials, with particular emphasis on process simplification and scalability.
